Vol 7 Issue 1

Spotlight

Preclinical/translational tools and strategies

Feb 2021

Guest Editor:

Bruce Bunnell, Professor and Chair at UNT Health Science Center

Foreword

Preclinical/translational tools & strategies

Bruce A Bunnell

24 February 2021

Foreword

Accelerating preclinical development for AAV based gene therapies: bridging the gap between discovery and clinical development

Louise Rodino-Klapac

24 February 2021

Editorial

Modelling late-onset diseases with induced pluripotent stem cells: a matter of time management

Charlotte Cossins,

Paul J Fairchild

15 February 2021

Expert Insight

The T cell therapy field faces preclinical and translational R&D challenges as it targets more complex diseases

Gary Waanders,

Silke Raffegerst,

Petra Prinz-Schulz,

Maja Buerdek

15 February 2021

Expert Insight

Animal models of disease: preclinical to clinical gene therapy translatability

Erika Matsumoto Plata,

Carlos R Plata-Salamán

11 February 2021

Expert Insight

Expediting novel <em>ex vivo</em> HSC gene therapies to the clinic: a preclinical perspective

Expediting novel ex vivo HSC gene therapies to the clinic: a preclinical perspective

Giulia Leoni,

Andy Lambert,

Charlotte Hudson,

Chiara Recchi,

Marina Cattoni,

Paul Heal

24 February 2021

Commentary

On a mission to bring single-cell sequencing to cell and gene therapy

Charlie Silver

24 February 2021

Interview

Beginning gene therapy preclinical development with the end in mind: from preclinical to economic modelling

Olivier Negre, PhD

16 February 2021

Interview

On a mission to bring single-cell sequencing to cell and gene therapy

Charlie Silver

24 February 2021

Podcast

Listen now

FastFacts

Identify and select optimal T cell phenotypes

James Lovrgen

22 February 2021

FastFacts

Business Insights January 2021

Expert Insight

Business Insight: cell & gene therapy

Jackie Mulryne,

Dr Beatriz San Martin,

John Schmidt,

Ewan Townsend

1 February 2021

Expert Insight

Innovator Insight

Optimization of AAV process development: transfection matters

Kelsey Wosnitzka,

Shandel Pariag ,

Hélène Trottin ,

Dr Alengo Nyamay’antu,

Mathieu Porte ,

Malik Hellal,

Patrick Erbacher

14 January 2021

Innovator Insight

A stepwise approach to process optimization in cellular immunotherapy development

Jim Lu

24 February 2021

Interview

Get in line: developing in-process analytical tools for gene therapy applications

René Gantier,

Ramsey Shanbaky,

Jay West

10 February 2021

Interview

Get in line: developing in-process analytical tools for gene therapy applications

René Gantier,

Ramsey Shanbaky,

Jay West

10 February 2021

Podcast

Listen now

Translation Insight

Flow cytometric analysis for cellular therapy products: design and practical considerations

Alison J Thomson,

Laura Bailey,

John DM Campbell

26 January 2021

Translation Insight

The importance of a strong collection cell collection network during the COVID-19 pandemic

Chris McClain, MBA

11 February 2021

FastFacts

Case study: Optimization of lentiviral vector production from early stages to GMP

Claire Wartel-Weill, Director of Quality and Compliance, Polyplus-transfection

Natalia Elizalde, Business Development Director, VIVEviotech

Rakel López de Maturana, Qualified Person, VIVEBiotech

19 January 2021

Webinar

Watch now

Breaking barriers in viral vector titer analysis speed, volume, and data quality

Robert Durham, PhD, Director of Service and Scientific Support, Gyros Protein Technologies

Johannes Stanta, PhD, Director of Bioanalysis, Freeline Therapeutics

Katherine Hanson, PhD, Lab Manager, PPD Laboratories

Judith Greengard, Senior Scientific Fellow, Exploratory Analytical Development and Validation, Adverum Biotechnologies, Inc.

27 January 2021

Webinar

Watch now

Supporting development of mRNA-based therapies by addressing large scale purification challenges

Kelly Flook, Senior Product Manager, Purification, Bioproduction Division, Thermofisher scientific

9 February 2021

Webinar

Watch now

Exploring the capabilities of a versatile, novel, automated closed system for cell and gene therapy manufacturing

Premkumar Jayaraman, PhD, Regional Field Application Scientist, APJ (Cell & Gene Therapy), Thermo Fisher Scientific

Sarah Daoudi, Scientist III, Field Applications, Thermo Fisher Scientific

16 February 2021

Webinar

Watch now

Large-scale LVV production: from industry-leading process development to high quality GMP vector

Dr Giuliana Vallanti , Director, Development and Global R&D, Cell and Gene, AGC Biologics

Professor Alessandro Aiuti , Deputy Director, Clinical Research, San Raffaele Telethon Institute for Gene Therapy (SR-TIGET)

Dr Marianna Sabatino , Head of Product Sciences, Autolus Ltd

25 February 2021

Webinar

Watch now

Harnessing the power of tumor-infiltrating lymphocytes for cell therapy

Dr Sandy Pelletier, Scientific Coordinator, Adoptive Cell Transfer (ACT) Immunotherapy Program, Centre de Recherche du Centre Hospitalier de l’Université de Montréal (CRCHUM)

Felix Eppler, PhD, Group Leader, Cell Sorting Product Management, Miltenyi Biotec

Niloufar Monhasery, Global Product Manager, Miltenyi Biotec

3 March 2021

Webinar

Watch now

CELL & GENE THERAPY INSIGHTS

Feb 2021. Vol 7 Issue 1

FEATURING

Spotlight

Preclinical/translational tools and strategies

Co-sponsor

Foreword

Preclinical/translational tools & strategies

Editorial

Accelerating preclinical development for AAV based gene therapies: bridging the gap between discovery and clinical development

Expert Insight

Modelling late-onset diseases with induced pluripotent stem cells: a matter of time management

The T cell therapy field faces preclinical and translational R&D challenges as it targets more complex diseases

Animal models of disease: preclinical to clinical gene therapy translatability

Commentary

Expediting novel ex vivo HSC gene therapies to the clinic: a preclinical perspective

Interview

On a mission to bring single-cell sequencing to cell and gene therapy

Beginning gene therapy preclinical development with the end in mind: from preclinical to economic modelling

Podcast

On a mission to bring single-cell sequencing to cell and gene therapy

FastFacts

Identify and select optimal T cell phenotypes

Report

Business Insights January 2021

Expert Insight

Business Insight: cell & gene therapy

Other articles

Innovator Insight

Optimization of AAV process development: transfection matters

Interview

A stepwise approach to process optimization in cellular immunotherapy development

Get in line: developing in-process analytical tools for gene therapy applications

Podcast

Get in line: developing in-process analytical tools for gene therapy applications

Translation Insight

Flow cytometric analysis for cellular therapy products: design and practical considerations

FastFacts

The importance of a strong collection cell collection network during the COVID-19 pandemic

Webinars

Case study: Optimization of lentiviral vector production from early stages to GMP

Breaking barriers in viral vector titer analysis speed, volume, and data quality

Supporting development of mRNA-based therapies by addressing large scale purification challenges

Exploring the capabilities of a versatile, novel, automated closed system for cell and gene therapy manufacturing

Large-scale LVV production: from industry-leading process development to high quality GMP vector

Harnessing the power of tumor-infiltrating lymphocytes for cell therapy