BioInsights - Vol 7 Issue 1

CELL & GENE THERAPY INSIGHTS

Vol 7 Issue 1

Cell & Gene Therapy Vol 7 Issue 1

Download PDF

Featuring

Issue Spotlight: Preclinical/translational tools and strategies
Other articles
Webinars

Preclinical/translational tools and strategies

Bruce Bunnell

Guest Editor:

Bruce Bunnell, Professor and Chair at UNT Health Science Center

Foreword

Preclinical/translational tools & strategies

Preclinical/translational tools & strategies

Bruce A Bunnell

24 February 2021

Editorial

Accelerating preclinical development for AAV based gene therapies: bridging the gap between discovery and clinical development

Accelerating preclinical development for AAV based gene therapies: bridging the gap between discovery and clinical development

Louise Rodino-Klapac

24 February 2021

Expert Insight

Modelling late-onset diseases with induced pluripotent stem cells: a matter of time management

Modelling late-onset diseases with induced pluripotent stem cells: a matter of time management

Charlotte Cossins, Paul J Fairchild

15 February 2021

The T cell therapy field faces preclinical and translational R&D challenges as it targets more complex diseases

The T cell therapy field faces preclinical and translational R&D challenges as it targets more complex diseases

G Waanders, S Raffegerst, P Prinz-Schulz et al.

15 February 2021

Animal models of disease: preclinical to clinical gene therapy translatability

Animal models of disease: preclinical to clinical gene therapy translatability

Erika Matsumoto Plata, Carlos R Plata-Salamán

11 February 2021

Commentary

Expediting novel <em>ex vivo</em> HSC gene therapies to the clinic: a preclinical perspective

Expediting novel ex vivo HSC gene therapies to the clinic: a preclinical perspective

G Leoni, A Lambert, C Hudson et al.

24 February 2021

Interview

On a mission to bring single-cell sequencing to cell and gene therapy

On a mission to bring single-cell sequencing to cell and gene therapy

Charlie Silver

24 February 2021

Beginning gene therapy preclinical development with the end in mind: from preclinical to economic modelling

Beginning gene therapy preclinical development with the end in mind: from preclinical to economic modelling

Olivier Negre, PhD

16 February 2021

Podcast

On a mission to bring single-cell sequencing to cell and gene therapy

On a mission to bring single-cell sequencing to cell and gene therapy

24 February 2021

FastFacts

Identify and select optimal T cell phenotypes

Identify and select optimal T cell phenotypes

James Lovrgen

22 February 2021

Journal articles

Expert Insight

Business Insight: cell & gene therapy

Business Insight: cell & gene therapy

J Mulryne, D San Martin, J Schmidt et al.

1 February 2021

Innovator Insight

Optimization of AAV process development: transfection matters

Optimization of AAV process development: transfection matters

K Wosnitzka, S Pariag, H Trottin et al.

14 January 2021

Interview

Get in line: developing in-process analytical tools for gene therapy applications

Get in line: developing in-process analytical tools for gene therapy applications

10 February 2021

A stepwise approach to process optimization in cellular immunotherapy development

A stepwise approach to process optimization in cellular immunotherapy development

24 February 2021

Podcast

Get in line: developing in-process analytical tools for gene therapy applications

Get in line: developing in-process analytical tools for gene therapy applications

R Gantier, R Shanbaky, J West

10 February 2021

FastFacts

The importance of a strong collection cell collection network during the COVID-19 pandemic

The importance of a strong collection cell collection network during the COVID-19 pandemic

Chris McClain, MBA

11 February 2021

Translation Insight

Flow cytometric analysis for cellular therapy products: design and practical considerations

Flow cytometric analysis for cellular therapy products: design and practical considerations

A Thomson, L Bailey, J Campbell

26 January 2021

Case study: Optimization of lentiviral vector production from early stages to GMP

Case study: Optimization of lentiviral vector production from early stages to GMP

C Wartel-Weill, N Elizalde, R de Maturana

19 January 2021

Breaking barriers in viral vector titer analysis speed, volume, and data quality

Breaking barriers in viral vector titer analysis speed, volume, and data quality

R PhD, J PhD, K PhD et al.

27 January 2021

Supporting development of mRNA-based therapies by addressing large scale purification challenges

Supporting development of mRNA-based therapies by addressing large scale purification challenges

Kelly Flook

9 February 2021

Exploring the capabilities of a versatile, novel, automated closed system for cell and gene therapy manufacturing

Exploring the capabilities of a versatile, novel, automated closed system for cell and gene therapy manufacturing

Premkumar Jayaraman, PhD, Sarah Daoudi

16 February 2021

Large-scale LVV production: from industry-leading process development to high quality GMP vector

Large-scale LVV production: from industry-leading process development to high quality GMP vector

D Vallanti, P Aiuti, D Sabatino

25 February 2021

Harnessing the power of tumor-infiltrating lymphocytes for cell therapy

Harnessing the power of tumor-infiltrating lymphocytes for cell therapy

D Pelletier, F PhD, N Monhasery