BioInsights - Vol 8 Issue 09

CELL & GENE THERAPY INSIGHTS

Vol 8 Issue 09

Cell & Gene Therapy Vol 8 Issue 09

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Featuring

Issue Spotlight: Gene therapy CMC and analytics
Focus: Downstream bioprocessing
Other articles
Webinars

Gene therapy CMC and analytics

Anindya Dasgupta

Guest Editor:

Anindya Dasgupta, Director of GMP at Expression

Expert Insight

Adeno-associated virus adsorption on different surfaces relevant to production of pre-clinical & clinical material

Adeno-associated virus adsorption on different surfaces relevant to production of pre-clinical & clinical material

A Zhang, S Cook, A Mayer

30 September 2022

Innovator Insight

Accelerating your AAV pathway to GMP & clinic

Accelerating your AAV pathway to GMP & clinic

James J Cody

A case study on streamlining AAV titer determination using variable pathlength technology

A case study on streamlining AAV titer determination using variable pathlength technology

Joe Ferraiolo, Yan Chen

31 October 2022

Transfection innovation for large-scale AAV & LV: considerations for process development through commercial manufacturing

Transfection innovation for large-scale AAV & LV: considerations for process development through commercial manufacturing

Leisha Kopp, Geddy Hamblen

9 November 2022

Interview

Addressing the shortfalls of low reproducibility, low throughput classical analytics for AAV manufacturing

Addressing the shortfalls of low reproducibility, low throughput classical analytics for AAV manufacturing

Chris Heger

6 September 2022

Glimpsing the future of AAV analytical innovation

Glimpsing the future of AAV analytical innovation

4 September 2022

FastFacts

High-throughput, automated analysis of viral vector titer and process-related impurities accelerates downstream process development of AAV-based gene therapies

High-throughput, automated analysis of viral vector titer and process-related impurities accelerates downstream process development of AAV-based gene therapies

29 September 2022

Downstream bioprocessing

FastFacts

High-throughput, automated analysis of viral vector titer and process-related impurities accelerates downstream process development of AAV-based gene therapies

High-throughput, automated analysis of viral vector titer and process-related impurities accelerates downstream process development of AAV-based gene therapies

29 September 2022

Innovator Insight

Addressing current challenges in lentiviral vector purification & associated analytics

Addressing current challenges in lentiviral vector purification & associated analytics

Bryan Zee, Anindya Dasgupta

16 January 2023

Improved lentivirus recovery by weak anion exchange capture

Improved lentivirus recovery by weak anion exchange capture

16 December 2022

Podcast

Improvement of viral vector purification using Mustang<sup>®️</sup> Q membrane chromatography

Improvement of viral vector purification using Mustang^®️ Q membrane chromatography

Journal articles

Expert Insight

Strategic partnering to enable cell therapy commercialization

Strategic partnering to enable cell therapy commercialization

Innovator Insight

Optimizing vector production and purification to enhance scalable AAV manufacturing

Optimizing vector production and purification to enhance scalable AAV manufacturing

J Zmuda, C Gaskin, J Molinari et al.

7 December 2022

Interview

Purification challenges & considerations with RNA & extracellular vesicles

Purification challenges & considerations with RNA & extracellular vesicles

22 November 2022

Podcast

Tales, tips & teachable moments from applications support veterans

Tales, tips & teachable moments from applications support veterans

C Suarez, C Siler, A Mogen

Expert Roundtable Video

Virtual Think-Tank on AAV vectors

Virtual Think-Tank on AAV vectors

31 October 2022

FastFacts

Leveraging the power of AI to design the best performing iPSC culture media

Leveraging the power of AI to design the best performing iPSC culture media

14 September 2022

Accelerate your development & understanding of viral & non-viral drug delivery vectors: from proof of concept to drug product manufacture

Accelerate your development & understanding of viral & non-viral drug delivery vectors: from proof of concept to drug product manufacture

11 October 2022

Poster

Selecting the right elution buffer for mRNA purification using the POROS Oligo (dT)25 Affinity Resin

Selecting the right elution buffer for mRNA purification using the POROS Oligo (dT)25 Affinity Resin

Jenny England

17 September 2022

Build vs buy dilemma: economics of manufacturing cell-based therapies

Build vs buy dilemma: economics of manufacturing cell-based therapies

23 September 2022

Strategic partnering to enable cell therapy commercialization: an ArsenalBio case study

Strategic partnering to enable cell therapy commercialization: an ArsenalBio case study

Jenessa Smith

4 November 2022

EBook

The Future of Cell and Gene Therapy: Experts’ Perspectives

The Future of Cell and Gene Therapy: Experts’ Perspectives

26 September 2022

Tailoring viral vector transgene optimization for enhanced efficacy

Tailoring viral vector transgene optimization for enhanced efficacy

Harrison Brown

27 October 2022

Navigating scalability and consistency in the allogeneic supply chain

Navigating scalability and consistency in the allogeneic supply chain

Anne Dircks, Dean Lee

1 November 2022

Viral vector manufacturing process - addressing bottlenecks with innovative solutions

Viral vector manufacturing process - addressing bottlenecks with innovative solutions

Rachel Legmann

8 November 2022

Improved lentivirus recovery by weak anion exchange capture

Improved lentivirus recovery by weak anion exchange capture

Lisa Marx, PhD

15 November 2022