Bridging the knowledge gap in donor cellular starting material quality & variability

David McCall, Commissioning Editor, BioInsights, talks to Yiran Zhou, Director of Process Development and Manufacturing, Cell Therapy, Sorrento Therapeutics

Yiran Zhou, PhD, majoring in Cell Biology and Biochemistry, currently serves as director of process development and cGMP manufacture in cell therapy at Sorrento Therapeutics. She has twenty years’ experience in cell biology with nearly eight years’ experience in cancer immunotherapy field. In her role, she leads process development and clinical product manufacturing activities, mostly focusing on allogeneic CAR-T therapy, including the strategy development of both upstream and downstream processing with the coverage from cellular starting material selection, cell activation, engineering, expansion to cell harvesting and fill/finish.

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