Jul
10
2018
On demand

Standardized techniques for navigating the cell and gene therapy supply chain

Delivering solutions to the challenges of manufacturing gene and cell therapies has never been so significant, as more products move towards commercialization. The supply chain for these potentially transformative therapies is uniquely complex, making it essential to understand and optimize the various components including standardization and risk mitigation with your outsourcing partners.

In this webinar, our panelists explore standardization techniques for the cell and gene therapy supply chain, addressing issues such as:

  • The feasibility of achieving standardization with so many elements to your supply chain logistics;
  • How we as an industry can approach standardization;
  • Advantages and disadvantages of outsourcing and managing your supplier relationships to minimize risk;
  • Key considerations when assessing which elements of your supply chain could or should be outsourced.

Jamie Margolis

Director of Product Development Operations at Be The Match BioTherapies

Director of Product Development Operations, Be The Match BioTherapies®Jamie Margolis is the Director of Product Development Operations for Be The Match BioTherapies, and has more than 9 years of experience managing the complexities of cellular therapies. Jamie and her team work closely with clients to understand their unique needs and determine how Be The Match BioTherapies can best support delivery of services based on client specifications. It is her team’s responsibility to ensure the smooth operational delivery of products and services to clients, such as supply chain management, development and management of collection networks, identifying and sourcing allogeneic donor cells, as well as regulatory compliance. She joined Be The Match BioTherapies’ parent organization, the National Marrow Donor Program/Be the Match, in 2009 and spent the first 6 years in patient case management supporting the operational needs of health care providers for stem cell transplant and troubleshooting unexpected disruptions that occur throughout the complex product delivery process. Jamie has worked for Be The Match BioTherapies since it was established in 2016. She holds her PhD in Molecular Biology and Genetics from the University of Minnesota.


Dr. Mark Dudley

SVP Bioprocessing & Development CMC, Technical Operations at Adaptimmune Therapeutics

Dr. Mark Dudley is a Senior Vice President at Adaptimmune Therapeutics, a leader in genetically modified T cell therapies for solid cancers, where he is responsible for manufacturing and development. Dr. Dudley has been a pioneer in the field of immunotherapy manufacturing, and has developed and implemented innovative early process design with accompanying analytics for multiple therapies. Previously, as Director of New Cell Products in the Cell and Gene Therapies division of Novartis Pharmaceutical Corp, Dr Dudley was responsible for establishing scalable, GMP-compliant production strategies and facilitating globalization of CAR-T products and platforms. As Director of the Cell Manufacturing Facility at the Surgery Branch of the National Cancer Institute, NIH, in Bethesda, MD, Dr Dudley investigated tumor rejection antigens, T cell specificity and function, and methods for the generation and administration to patients of T cell therapies. His work has resulted in more than 100 peer-reviewed publications, and he is co-author on numerous seminal papers including early tumor-infiltrating lymphocytes studies demonstrating that adoptive T-cell transfer has tumor eradicating potential. Dr. Dudley earned a PhD in Biological Sciences at Stanford University, and had post-doctoral fellowships at The University of Pennsylvania in Philadelphia, PA and at the Jackson Laboratory in Bar Harbor, ME.

SPEAKERS

Jamie Margolis
Director, Cell & Gene Therapy at Be The Match BioTherapies
Dr. Mark Dudley
Senior Vice President Early Development, Adaptimmune

You might also like

Thinking translational: Things to consider in CAR T cell research workflows

S Rösch, PhD
Saskia Rösch, PhD
Saskia Rösch, PhD
Global Product Manager at Miltenyi Biotec
22 Jun 2022
36
Days
7
Hrs
9
Min
Register

Accelerating cell therapy discovery & development with non-viral gene...

D Hermanson
X Patrinostro
David Hermanson
David Hermanson
Senior Manager of R&D Applications, Cell and Gene Therapy at Bio-techne
Xiaobai Patrinostro
Xiaobai Patrinostro
Manager of Genome Engineering Services, Cell and Gene Therapy at Bio-techne
16 Jun 2022
29
Days
15
Hrs
9
Min
Register

Life on a chip - vascularized micro-tumor chips for mimicking clinical...

C Hughes
Chris Hughes
Chris Hughes
CSO at Aracari Biosciences
8 Jun 2022
22
Days
7
Hrs
9
Min
Register

Monitoring of circulating CAR T cells

A Graband,
D Hünecke,
D Bremm
Annika Graband
Annika Graband
Product Manager, Cell Analysis Reagents at Miltenyi Biotec
Dr. Sabine Hünecke
Dr. Sabine Hünecke
Head of Laboratory, Stem Cell Transplantation and Immunotherapy at University Hospital Frankfurt
Dr. Melanie Bremm
Dr. Melanie Bremm
Deputy Head of Laboratory, Stem Cell Transplantation and Immunotherapy at University Hospital Frankfurt
31 May 2022
14
Days
7
Hrs
9
Min
Register

Improving T cell therapy manufacturing processes with automation and...

E Zynda, PhD
Evan Zynda, PhD
Evan Zynda, PhD
Staff Scientist, Cell Biology at Thermo Fisher Scientific
26 May 2022
9
Days
7
Hrs
9
Min
Register