Advancing engineered cell & gene therapy with precision gene editing

Immuno-Oncology Insights 2022; 3(1), 37–49


Published: 26 January 2022
Innovator Insight
John Lambourne

The increased range and accessibility of gene modification technologies has had a great impact on the cell and gene therapy field, with CRISPR-Cas9 in particular garnering increased attention in the last decade. But is it always the best tool for the job? In this article, CRISPR and base editing techniques will be compared – demonstrating the key advantages base editing technology can offer to the field in terms of safety and efficiency, and how increasingly precise gene editing approaches can help to deliver the next generation of advanced therapies.