This month, Nucleic Acid Insights concentrates on emerging modalities in the oligonucleotide therapeutics space, including a focus on the relationship between sequence and chemistry and how that impacts the properties of novel oligo-based medicines. In addition, we place a spotlight on the potential of cutting-edge extracellular vesicle delivery platforms to open up new opportunities for the nucleic acid therapeutics field.

In this month's edition, we explore nonclinical tools and technologies being employed in the clinical translation of mRNA therapeutics, and investigate the key challenge of enhancing the stability of nucleic acid drugs in vivo.

This month, Nucleic Acid Insights explores platform approaches for oligonucleotide manufacturing, the evolution of saRNA for clinical applications, and enhancing nanoparticle-based drug delivery.

Issue Spotlight: mRNA processing and analysis

This month, Nucleic Acid Insights explores issues in the targeting and delivery of oligonucleotides, and challenges in the LNP field

Issue Spotlight: Delivery and formulation

Issue Spotlight: Launch Edition